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Search Results for " atp-sensitive potassium "

20

Compounds

Cat No. Product Name Synonyms Targets
T15385 Glibornuride Potassium Channel
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent.
T9714 Atpenin A5 Potassium Channel
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].
T1603 Glipizide CP 28720,K 4024 Potassium Channel , PPAR , ABC
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.
T1634 Glibenclamide Glyburide Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
T1101 Minocycline hydrochloride Minocycline HCl HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...
T10566 BMS-191095 Potassium Channel
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
T21478 Cromakalim BRL-34915,BRL 34915,(±)-Cromakalim,BRL34915
Cromakalim, a potassium channel-opening vasodilator, acts on ATP-sensitive potassium channels and so causes membrane hyperpolarization, it can be used to treat hypertension as it will relax vascular smooth muscle to lowe...
T23563 ZM 226600 Potassium Channel
ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.
T16420 P-1075 Potassium Channel
P-1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species causing cardioprotection of rabbit hearts. P-1075 is an effective activator of sulfonylurea receptor 2-associated ATP-sensitive potassium c...
T26086L 1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one Others
1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one is an isomer of Rilmakalim, a potassium channel opener (PCO), which can activate ATP-sensitive K+ channels in the heart or other tissues
T3929 Kaurenoic acid Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid Others
Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...
T27624 Iptakalim Hydrochloride Potassium Channel , AChR
Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2...
T35107 Way 120491 Way120491,Way-120,491,Way-120491,Celikalim
Way 120491 activates ATP-sensitive potassium channels.
T71929 Clamikalant
Clamikalant inhibits ATP-sensitive potassium channel.
T70801 ZM-181037
ZM-181037 is an ATP-sensitive potassium channel-blocker and a eukalemic diuretic.
T11243 Ethyl tosylcarbamate Others
Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Ethyl tosylcarbamate is an intermediate in the synthesis of Gliclazide (G409877).
T68745 U 56324
U-56324 is a hypoglycemic agent derived from nicotinic acid. It was found to inhibit the activity of ATP-sensitive potassium channels in excised patches from mouse pancreatic B-cells.
T68602 AZ-DF 265
AZ-DF 265 is a hypoglycaemic drug which stimulates insulin release. AZ-DF-265 inhibits ATP-sensitive potassium channels and displaces [3H]-glibenclamide from the sulphonylurea receptor.
T63330 Clamikalant sodium
Clamikalant sodium is a non-selective, ATP-sensitive potassium (KATP) channel blocker that can be used to study cardiac arrhythmias.
T75084 Foslevcromakalim
Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].
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